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目的 :探讨脂蛋白 (a) [LP(a) ]与颈动脉粥样硬化 (AS)及缺血性脑卒中之间的关系。方法 :对 80例缺血性脑卒中患者 ,68例高血压病患者 ,60例 2型糖尿病患者及 5 5例健康人进行颈动脉超声检查 ,同时测定血浆LP(a)的浓度。结果 :AS者LP(a)明显高于颈动脉超声阴性者 ,缺血性脑卒中、高血压及 2型糖尿病患者斑块明显增加 ,动脉狭窄明显及LP(a)值明显增高 ,其中以缺血性脑卒中增高尤为显著。结论 :LP(a)异常增高能促进AS形成 ,与缺血性脑卒中的发病密切相关。
Objective: To investigate the relationship between lipoprotein (a) [LP (a)] and carotid atherosclerosis (AS) and ischemic stroke. Methods: Carotid ultrasonography was performed in 80 patients with ischemic stroke, 68 patients with hypertension, 60 patients with type 2 diabetes mellitus and 55 healthy controls. Plasma LP (a) concentrations were also measured. Results: The AS (LP) of AS was significantly higher than that of carotid ultrasound. The plaque of ischemic stroke, hypertension and type 2 diabetes mellitus were significantly increased. The stenosis of arteries and LP (a) were significantly increased, Bloody stroke is particularly significant increase. Conclusion: The abnormal increase of LP (a) can promote the formation of AS, which is closely related to the onset of ischemic stroke.