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目的观察天芪降糖胶囊对预防糖耐量减低(ICT)患者向2型糖尿病(T2DM)发展的效果。方法 216例ICT患者,随机分为2组,分别口服天芪降糖胶囊(TQ组,110例)和对照组(Con组,106例),观察治疗后血糖变化及转化为正常血糖和T2DM的比例。结果天芪降糖胶囊治疗后服糖2h血糖(2hPG)值明显低于基线值(P=0.000),且2hPC下降幅度大于Con组(P<0.005);与Con组相比,天芪降糖胶囊使T2DM发生风险下降56%。结论天芪降糖胶囊可显著降低ICT患者向T2DM发展的风险。
Objective To observe the effect of Tianqijiangtang Capsule in preventing the development of type 2 diabetes mellitus (T2DM) in patients with impaired glucose tolerance (ICT). Methods A total of 216 cases of ICT patients were randomly divided into 2 groups: oral administration of Tianqi Jiangtang Capsule (TQ group, 110 cases) and control group (Con group, 106 cases). The changes of blood glucose and the changes of normal blood glucose and T2DM proportion. Results Tianqi Jiangtang Capsule treatment 2h glucose (2hPG) value was significantly lower than the baseline (P = 0.000), and 2hPC decreased more significantly than the Con group (P <0.005); compared with the Con group, Tianqi hypoglycemic Capsules reduced the risk of T2DM by 56%. Conclusion Tianqijiangtang capsule can significantly reduce the risk of developing T2DM for ICT patients.