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目的:研究缺血性脑卒中患者急性期和恢复期血液流变学变化。方法:使用全自动血液粘度分析仪分别对20名缺血性脑卒中急性期患者,20名缺血性脑卒中恢复期患者及20名健康人的血液流变学进行检测。结果:缺血性脑卒中患者急性期,全血黏度明显增高(P<0.01),相对血液黏度在部分切变率上高于对照组(P<0.05);恢复期的全血粘度变化不明显,而相对血液粘度在各切变率上均低于对照组(P<0.05);急性期与恢复期的血浆黏度和纤维蛋白原含量均明显增高(P<0.01)。结论:缺血性脑卒中急性期是一个高粘滞状态,通过治疗或机体自身的反馈机制,恢复期患者的血液相对粘度降低,血液循环得到改善。
Objective: To study the changes of hemorheology in acute and convalescent ischemic stroke patients. Methods: The hemorheology of 20 acute ischemic stroke patients, 20 ischemic stroke recovery patients and 20 healthy volunteers were detected by automatic blood viscosity analyzer. Results: In the acute stage of ischemic stroke, the whole blood viscosity was significantly increased (P <0.01), and the relative blood viscosity was higher at the partial shear rate than that of the control group (P <0.05). The whole blood viscosity did not change significantly during the recovery period , While the relative blood viscosity was lower than that of the control group at all shear rates (P <0.05). The plasma viscosity and fibrinogen contents in both acute phase and convalescent phase were significantly increased (P <0.01). CONCLUSION: The acute phase of ischemic stroke is a high-viscosity state. The relative viscosity of blood in convalescent patients decreases and the blood circulation is improved by treatment or the body’s own feedback mechanism.