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目的:探讨杏丁注射液联合二甲双胍治疗2型糖尿病胰岛素抵抗的临床疗效。方法:2型糖尿病胰岛素抵抗患者,随机分为治疗组和对照组各30例,治疗组应用二甲双胍联合杏丁注射液治疗,对照组单纯二甲双胍治疗,比较两组患者的血糖和胰岛素敏感指数的改变。结果:治疗组患者的血糖改善明显优于对照组(P<0.05);胰岛素敏感指数改善与对照组比较有统计学意义(P<0.01)。结论:杏丁注射液联合二甲双胍治疗2型糖尿病,可以改善患者的胰岛素抵抗,临床疗效满意,值得临床推广。
Objective: To investigate the clinical efficacy of Xingding injection combined with metformin in the treatment of type 2 diabetes mellitus with insulin resistance. Methods: Patients with type 2 diabetes mellitus with insulin resistance were randomly divided into treatment group (30 cases) and control group (30 cases). Metformin and Xingding injection were used in the treatment group. Metformin alone was used in the control group. The changes of blood glucose and insulin sensitivity index . Results: The improvement of blood glucose in the treatment group was significantly better than that in the control group (P <0.05). The improvement of insulin sensitivity index was statistically significant compared with the control group (P <0.01). Conclusion: Xingding injection combined with metformin in the treatment of type 2 diabetes mellitus can improve insulin resistance in patients with satisfactory clinical results, which is worthy of clinical promotion.