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目的:通过观察自拟益气活血汤对老年高血压颈动脉粥样硬化病变患者血脂、血管活性物质、颈总动脉内膜中膜(IMT)、颈总动脉血流量以及临床症状的干预,论证益气活血汤是治疗老年高血压颈动脉粥样硬化病变的基本治疗方法。方法:采用随机分组法将患者分为治疗组25例和对照组25例,2周为1个疗程,共进行3个疗程。结果:治疗组在降压疗效、颈总动脉IMT、粥样斑块及血流量改善疗效、临床症状总疗效优于对照组,并有统计学意义。结论:益气活血汤是治疗老年高血压颈动脉粥样硬化病变的有效的基本治疗方法。
Objective: To observe the intervention of self-made Yiqi Huoxue Decoction on blood lipids, vasoactive substances, carotid intima-media thickness (IMT), common carotid artery blood flow and clinical symptoms in elderly patients with carotid atherosclerosis. Yiqihuoxue Decoction is the treatment of elderly patients with atherosclerosis of hypertension essential treatment. Methods: The patients were divided into treatment group (n = 25) and control group (n = 25) by random grouping method. One course of treatment was 2 weeks and a total of 3 courses were performed. Results: The curative effect of antihypertensive therapy, common carotid artery IMT, atherosclerotic plaque and blood flow were improved in the treatment group, and the total clinical effect was better than that in the control group, with statistical significance. Conclusion: Yiqi Huoxue Decoction is an effective and basic treatment for the treatment of carotid atherosclerosis in elderly patients with hypertension.