目的了解高碘地区重点人群碘营养状况以及病情变化趋势。方法选取居民饮用水水碘中位数在150～300μg/L的3个高碘乡,监测8～10岁儿童尿碘含量、8～10岁儿童甲状腺肿大情况(B超法)、居民饮用水碘含量、居民户盐碘含量。结果本次共应用B超检8～10岁儿童643人,甲状腺肿大47人,平均肿大率为7.31%。检测8～10岁儿童尿碘323份,尿碘中位数456.7μg/L。水碘39份,水碘中位数为256.4μg/L。居民户盐样320份,无碘盐率为78.4%。结论衡水市水源性高碘地区8～10岁儿童碘营养过量,儿童甲肿率处于较高发病水平,重点人群受高碘危害较为严重,形势不容乐观。应进一步加强改水及无碘盐供应管理,确保高碘地区群众健康。 Objective To understand the iodine nutrition status and the trend of disease in key population in high iodine area. Methods The iodine content in urine of 8 ~ 10 years old children, thyroid enlargement of 8 ~ 10 years old children (B super-law) was monitored by drinking water iodine median of 150 ~ 300μg / L, Water iodine content, household salt iodine content. Results A total of 643 children aged 8-10 years old were examined by B-mode ultrasonography and 47 were goiter. The average rate of enlargement was 7.31%. The urine iodine was detected in 323 children aged 8-10 years with a median urinary iodine of 456.7μg / L. 39 parts of water iodine, median water iodine 256.4μg / L. Resident households 320 samples of salt, salt-free rate of 78.4%. Conclusion In iodine-deficient areas of Hengshui City, children aged 8 ~ 10 years have excessive iodine nutrition and children’s goiter rate is at a higher level. The key population is more seriously affected by high-iodine, and the situation is not optimistic. Should be further strengthened water and non-iodized salt supply management, to ensure that people in high iodine area health.