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目的了解脑卒中患者合并肾功能不全的情况,并探讨脑卒中与慢性肾功能不全的关系。方法回顾性分析我院收治的486例首次入院的脑卒中患者的临床资料,观察患者性别、年龄、民族、既往史及颈动脉情况;采用肾脏疾病饮食调整研究法求估测的肾小球滤过率;按照K/DOQI指南的分期标准,慢性肾功能不全判定标准为肾小球滤过率<60 ml.min-1.(1.73 m2)-1,按照美国国立卫生研究院卒中量表评估患者神经功能缺损程度。结果 486例脑卒中患者中121例合并肾功能不全,占24.9%。肾功能不全组与非肾功能不全组性别构成及原发性高血压病史、血脂异常、高尿酸血症、颈动脉内膜增厚、颈动脉斑块的发生率比较,差异均有统计学意义(P<0.05)。肾功能不全组脑出血及非腔隙性脑梗死的发生率与非肾功能不全组比较,差异均有统计学意义(P<0.05)。脑卒中合并慢性肾功能不全患者神经功能缺损程度与非肾功能不全患者比较,差异有统计学意义(u=3.609,P=0.000)。结论脑卒中患者合并肾功能不全发生率较高,提示慢性肾功能不全是判断新发脑卒中患者预后的重要因素。
Objective To understand the situation of patients with stroke complicated with renal insufficiency and to explore the relationship between stroke and chronic renal insufficiency. Methods The clinical data of 486 first-episode stroke patients admitted to our hospital were retrospectively analyzed. The gender, age, nationality, past history and carotid artery status were observed. The estimated glomerular filtration rate According to the K / DOQI guidelines, the criterion of chronic renal insufficiency was glomerular filtration rate <60 ml.min-1. (1.73 m2) -1. According to the National Institutes of Health Stroke Scale Patients with neurological deficits. Results Among the 486 stroke patients, 121 cases had renal insufficiency, accounting for 24.9%. Renal dysfunction group and non-renal dysfunction in patients with gender composition and history of primary hypertension, dyslipidemia, hyperuricemia, carotid intimal thickening, the incidence of carotid plaques, the differences were statistically significant (P <0.05). Renal dysfunction group of cerebral hemorrhage and non-lacunar infarction incidence and non-renal dysfunction group, the difference was statistically significant (P <0.05). The difference of neurological deficit between patients with stroke and chronic renal insufficiency was statistically significant (u = 3.609, P = 0.000). Conclusions The incidence of renal dysfunction in stroke patients is high, suggesting that chronic renal insufficiency is an important factor in judging the prognosis of new stroke patients.