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美国化学家罗森博格(Barnett Rosenberg)偶然发现了顺铂对细胞分裂的抑制作用,揭开了铂类配合物抗肿瘤治疗的序幕。历经第一代(顺铂)、第二代(卡铂、奈达铂)和第三代铂类药物(奥沙利铂、洛铂),铂类抗肿瘤药终于一步步接近了高效、低毒、不交叉耐药的理想。洛铂作为第三代铂类抗肿瘤药,因其良好的抗肿瘤效果和更佳的患者耐受性,顺利进入
American chemist Barnett Rosenberg accidentally discovered the inhibitory effect of cisplatin on cell division, opened the prelude to anti-cancer treatment of platinum complexes. After the first generation (cisplatin), second generation (carboplatin, nedaplatin) and the third generation of platinum drugs (oxaliplatin, lobaplatin), platinum anti-cancer drugs finally step by step approach to efficient, low Poisonous, not cross-resistant ideal. Loboplatin as the third generation of platinum anti-tumor drugs, because of its good anti-tumor effect and better patient tolerance, successfully entered