新麻滴鼻剂是由硫酸新霉素、盐酸麻黄碱及尼泊金乙酯等组成的水溶液，用于慢性鼻炎，化脓性鼻窦炎等。麻黄碱的含量测定多采用比色法、一阶导数法等．本文根据文献采用多波长吸收度比值差法，不经分离直接测定盐酸麻黄碱的含量，能很好地消除尼泊金的干扰，操作简便，适合医院 Nemata nasal drops by the neomycin sulfate, ephedrine hydrochloride and ethyl paraben and other components of the aqueous solution for chronic rhinitis, purulent sinusitis. Ephedrine content determination using colorimetric method, the first derivative method. In this paper, according to the literature using multi-wavelength absorbance ratio difference method, direct determination of the content of ephedrine hydrochloride without separation, can well eliminate the interference of nipagin, easy to operate, suitable for hospitals