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目的探讨米非司酮配伍米索前列醇终止10~14周妊娠的临床效果,减少流产并发症。方法将138例自愿要求终止10~14周妊娠的健康妇女分为两组:药流组86例,口服米非司酮50mg共4次,第3天口服米索前列醇0.6mg;钳刮组52例,术前1d宫颈管内插管,次日行钳刮人流术,比较两种方法的临床效果。结果药流组在流产中及流产后阴道流血量及持续时间、宫体压痛、感染均少于钳刮组,P<0.05,有统计学意义,而子宫复旧,月经复潮及月经规则要早于钳刮组。结论米非司酮配伍米索前列醇是目前最佳终止10~14周妊娠的流产方式。
Objective To investigate the clinical effect of mifepristone combined with misoprostol to terminate the pregnancy of 10 to 14 weeks to reduce the complications of abortion. Methods A total of 138 healthy women who volunteered to terminate pregnancy from 10 to 14 weeks were divided into two groups: drug-flow group (86 cases), oral mifepristone (50 mg) 4 times and oral misoprostol 0.6 mg on day 3 For example, 1 d preoperative cervical intubation, the next line of forceps scraped abortion, comparing the clinical effects of the two methods. Results The rate of vaginal bleeding and duration of abortion and post-abortion vaginal bleeding in the abortion group were lower than those in the shaving group (P <0.05), while the rates of uterine involution, menstruation and menstruation were earlier than Pliers scraping group. Conclusion Mifepristone combined with misoprostol is the best termination of pregnancy 10-14 weeks of abortion.