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目的:探讨肾嗜酸细胞腺瘤(renal oncocytoma,RO)的临床及病理学特点,提高对该病的诊治水平。方法:回顾性分析我院2008~2014年收治的7例RO患者的临床资料:男3例,女4例,年龄30~63岁,平均40岁。5例因体检发现,2例因腰部酸痛不适就诊发现;7例行CT、MRI、超声等影像学检查均有阳性发现。肿瘤均为单侧单发,位于左肾6例,右肾1例。肿瘤直径在2.5~10cm,平均5.06cm。6例行肾脏部分切除术,1例行肾肿瘤根治性切除术。结果:本组7例患者均痊愈出院。其中1例失访,6例随访,随访时间2~56个月,中位随访时间45个月,均未发现肿瘤复发或远处转移。术后病理检查报告均为RO。结论:RO是一种少见的肾脏良性肿瘤,多无临床表现,影像学检查均有阳性发现,典型病例有特异性影像学表现,但大多无特异性表现。不推荐术前穿刺活检,术中快速冷冻切片检查有一定意义。确诊有赖于病理检查及免疫组织化学分析。治疗上以保留肾单位手术为首选,术后需定期随访。
Objective: To investigate the clinical and pathological characteristics of renal oncocytoma (RO) and to improve the diagnosis and treatment of the disease. Methods: The clinical data of 7 patients with RO admitted from 2008 to 2014 in our hospital were retrospectively analyzed. There were 3 males and 4 females, aged from 30 to 63 years, with an average of 40 years. Five cases were found by physical examination, two cases were found due to the pain and discomfort of the waist. Seven cases were found by imaging examination such as CT, MRI and ultrasound. Tumors were unilateral single, located in the left kidney in 6 cases, 1 case of right kidney. Tumor diameter 2.5 ~ 10cm, an average of 5.06cm. 6 cases of partial nephrectomy, 1 case of radical resection of renal tumors. Results: All seven patients in this group were discharged. One case was lost to follow-up, 6 cases were followed up for 2 to 56 months. The median follow-up time was 45 months. No tumor recurrence or distant metastasis was found. Postoperative pathological examination reports are RO. Conclusion: RO is a rare benign renal neoplasm. It has no clinical manifestations and has positive findings in imaging examination. Typical cases have specific imaging findings, but most of them are nonspecific. Preoperative biopsy is not recommended, intraoperative rapid frozen biopsy has some significance. Diagnosis depends on the pathological examination and immunohistochemical analysis. Treatment of nephron surgery to retain the first choice, regular follow-up after surgery.