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目的探讨联合用药在原发性高血压治疗中的应用价值。方法选取78例原发性高血压患者联合用药的临床疗效,随机分成观察组和对照组,每组39例。对照组患者采用缬沙坦治疗,观察组在缬沙坦治疗基础上联合应用硝苯地平缓释片治疗,治疗8周后,对2组患者的临床疗效及药物不良反应比较。结果观察组总有效率为94.9%,显著高于对照组的82.1%(P<0.01);观察组不良反应总发生率为7.7%,明显低于对照组的17.9%(P<0.01)。结论联合用药治疗原发性高血压,疗效确切,药物不良反应少,值得临床推广。
Objective To explore the value of combination therapy in the treatment of essential hypertension. Methods The clinical efficacy of combination therapy in 78 patients with essential hypertension was randomly divided into observation group and control group, 39 cases in each group. Patients in the control group were treated with valsartan. The observation group was treated with valsartan in combination with nifedipine sustained-release tablets. After 8 weeks of treatment, the clinical efficacy and adverse drug reactions of the two groups were compared. Results The total effective rate in the observation group was 94.9%, significantly higher than that in the control group (82.1%, P <0.01). The overall incidence of adverse reactions in the observation group was 7.7%, which was significantly lower than that in the control group (17.9%, P <0.01). Conclusion Combined treatment of essential hypertension, curative effect is accurate, less adverse drug reactions, it is worth clinical promotion.