论文部分内容阅读
为了研究大肠癌中nm23-H_1的表达与浸润转移的关系,本文应用链霉菌素-生物素(LSAB)免疫组织化学方法检测74例大肠癌中nm23-H_1和Ⅳ型胶原的表达.结果发现大肠癌中nm23-H_1阳性率为71.6%,nm23-H_1低表达与淋巴结转移有关(P<0.025)nm23-H_1的表达在Ⅳ型胶原表达不同肠癌中无明显差异(P>0.05).结果:nm23-H_1低表达可能仅在大肠癌转移过程中发挥作用.
In order to study the relationship between nm23-H1 expression and invasion and metastasis in colorectal cancer, the expression of nm23-H_1 and type IV collagen in 74 cases of colorectal cancer was detected by streptavidin-biotin (LSAB) immunohistochemical method. The positive rate of nm23-H_1 in cancer was 71.6%. The low expression of nm23-H_1 was associated with lymph node metastasis (P<0.025). The expression of nm23-H_1 had no significant difference in the expression of type IV collagen (P>0.05). The low expression of nm23-H_1 may only play a role in the metastasis of colorectal cancer.