论文部分内容阅读
目的:研究老年人胃癌术后早期肠内营养支持的安全性和合理性。方法:选择年龄60岁以上胃癌手术的26例患者随机分为肠内营养(EN)组和肠外营养(PN)组,每组13例。检测手术前后人体测量学指标及血红蛋白(Hb)、血浆白蛋白(Alb)、转铁蛋白(TFN)和纤维连接蛋白(FN)进行比较,同时观察胃肠功能恢复情况。两组营养支持均等热量。结果:术后两组的人体测量学指标和Hb、Alb进行比较,均无显著性意义(P>0.05);术后第8天病人均由负氮平衡转为正氮平衡;同时术后第4、8天时两组的FN提高比术前明显(P<0.05﹑P<0.01),而且术后第8天时EN组的上升比PN组更明显(P<0.05);肛门排气时间EN组比PN组为早(P<0.05)。结论:老年人胃癌术后给予早期肠内营养支持,可促进病人胃肠功能的恢复和改善营养代谢,是安全有效的。
Objective: To study the safety and rationality of early postoperative enteral nutrition support for elderly patients with gastric cancer. Methods: Twenty-six patients undergoing surgery for gastric cancer over the age of 60 were randomly divided into enteral nutrition (EN) group and parenteral nutrition (PN) group, 13 patients in each group. Hb, Alb, TFN and fibronectin (FN) were measured before and after the operation. The recovery of gastrointestinal function was also observed. Two groups of nutrition support equal calories. Results: There was no significant difference between the two groups in anthropometric indexes and Hb and Alb (P> 0.05). On the 8th day after operation, the patients turned from negative nitrogen balance to positive nitrogen balance. At the same time, The levels of FN in both groups were significantly higher than those before operation at 4 and 8 days (P <0.05, P <0.01), and the EN group increased more significantly than the PN group on the 8th day after operation (P <0.05) As early as PN group (P <0.05). Conclusion: It is safe and effective for elderly patients with gastric cancer to give early enteral nutrition support after surgery to promote the recovery of gastrointestinal function and improve nutritional metabolism.