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神经鞘磷脂(sphingomyelin,SM)是细胞膜的重要组成成分,是生成参与信号转导的神经酰胺(ceramide,CER)的主要来源。神经鞘磷脂酶(sphingomyelinase,SMase)是一种可催化神经鞘磷脂水解,生成CER和磷酸胆碱的酶。
Sphingomyelin (SM) is an important component of cell membrane and is the main source of generating ceramide (CER) involved in signal transduction. Sphingomyelinase (SMase) is an enzyme that catalyzes the hydrolysis of sphingomyelin to produce CER and phosphorylcholine.