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目的:研究单纯性肥胖症儿童的发生率及其血液流变学、血脂变化。方法:对准东地区3～12岁儿童进行单纯性肥胖症的群体调查,应用全自动血黏度分析仪和生化仪检测50例中、重度单纯性肥胖儿童(肥胖组)和40名正常体重健康儿童(对照组)的血液流变学和血脂指标。结果:准东地区儿童单纯性肥胖症的发生率为8%。其中轻度占49%,中度占26%,重度占25%。肥胖组的甘油三酯、总胆固醇、LDL-C分别为(0.9±0.1)mmol/L、(5±1)mmol/L、(1.9±0.3)mmol/L,对照组相应为(0.7±0.1)mmol/L、(4±1)mmol/L、(1.7±0.3)mmol/L;肥胖组的血浆黏度、红细胞刚性指数分别为(1.77±0.25)mPa·s、(3.89±0.55),对照组相应为(1.52±0.20)mPa·s、(3.54±0.48),两组的血液流变学指标及血脂指标的差异有统计学意义(均为P<0.05),表现为肥胖组的血浆黏度增高、红细胞变形能力减低及血脂增高。结论:单纯性肥胖症儿童出现血液流变学改变和脂代谢紊乱,提示单纯性肥胖症对心血管功能有潜在的危害,是成人肥胖症、心血管疾病的危险因子,故应及早预防,加以重视。
Objective: To study the incidence of obesity in children and its hemorheology, blood lipid changes. Methods: A total of 50 obese and moderately obese children (obese group) and 40 healthy people of normal weight were enrolled in this study. Hemorheology and lipids in children (control group). Results: The prevalence of simple obesity in children in Zhundong area was 8%. Among them, 49% are mild, 26% are moderate and 25% are severe. The levels of triglyceride, total cholesterol and LDL-C in obesity group were (0.9 ± 0.1) mmol / L, (5 ± 1) mmol / L and (1.9 ± 0.3) mmol / L respectively ), mmol / L, (4 ± 1) mmol / L and (1.7 ± 0.3) mmol / L respectively. The plasma viscosity and erythrocyte rigidity index were (1.77 ± 0.25) mPa · s and (3.89 ± 0.55) (1.52 ± 0.20) mPa · s and (3.54 ± 0.48) respectively. There was significant difference between the two groups in the hemorheology index and the blood lipid index (all P <0.05), which showed that the plasma viscosity Increased, reduced erythrocyte deformability and increased blood lipids. Conclusion: The changes of hemorheology and lipid metabolism in children with simple obesity suggest that simple obesity has potential harm to cardiovascular function and is a risk factor for obesity and cardiovascular disease in adults. Therefore, it should be prevented as soon as possible, Pay attention.