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目的观察在常规治疗的基础上加用曲美他嗪对改善老年性缺血性扩张型心肌病心力衰竭的疗效。方法将40例符合诊断标准的老年性缺血性扩张型心肌病的患者随机分为常规治疗组(对照组)和曲美他嗪治疗组(治疗组),两组疗程均为20周,比较两组治疗前后的临床疗效、心功能分级、LVEF值、心胸比等。结果曲美他嗪治疗组临床心功能分级明显改善,LVEF值显著提高,而血压、心率无影响。结论曲美他嗪治疗能明显改善老年性缺血性扩张型心肌病患者心功能。
Objective To observe the effect of trimetazidine combined with conventional therapy on heart failure in elderly patients with ischemic dilated cardiomyopathy. Methods 40 patients with diagnostic criteria of ischemic dilated cardiomyopathy were randomly divided into routine treatment group (control group) and trimetazidine treatment group (treatment group), the two courses of treatment were 20 weeks, compared Before and after treatment in both groups clinical efficacy, cardiac function classification, LVEF value, cardiothoracic ratio. Results Trimetazidine treatment group significantly improved the clinical cardiac function classification, LVEF increased significantly, but no effect of blood pressure, heart rate. Conclusion Trimetazidine treatment can significantly improve cardiac function in elderly patients with ischemic dilated cardiomyopathy.