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目的:比较丙泊酚复合芬太尼和笑气在人流术的镇痛效果和其它作用。方法:门诊人流患者100例,随机分为两组,A组(丙泊酚复合芬太尼)和B组(笑气组),A组先静注芬太尼1μg/kg,随后注射丙泊酚1.5 mg/g,B组用50%笑气和50%氧气混合气体使用无痛分娩仪。观察①两组患者术前、术中MAP、HR、SPO2;②手术中镇痛的效果;③患者术后清醒时间;④患者离院时间;⑤术后不良反应。结果:A组术中与术前的MAP、HR、SPO2有明显下降,与同期的B组数据相比有显著性差异(P<0.05),A组镇痛率为100%,B组为38%,两组有显著性差异(P<0.05),A组患者术中均无意识,患者离院时间长于B组,两组有显著性差异(P<0.05),两组患者术后不良反应,无显著性差异。结论:A组人流术镇痛效果好,相对B组更适合无痛人工流产。
OBJECTIVE: To compare the analgesic effects and other effects of propofol combined with fentanyl and nitrous oxide on abortion. Methods: One hundred outpatients were randomly divided into two groups: group A (propofol combined with fentanyl) and group B (nitrous oxide group). Group A received intravenous injection of fentanyl (1 μg / kg) Phenol 1.5 mg / g, B group with 50% nitrous oxide and 50% oxygen mixed gas using painless childbirth instrument. Observation ①The preoperative and postoperative MAP, HR, SPO2 of the two groups of patients; ② The effect of analgesia during the operation; ③The time of postoperative awake; ④The time of leaving hospital; ⑤Adverse reaction after operation. Results: The intraoperative and preoperative MAP, HR and SPO2 were significantly decreased in group A compared with those in group B at the same period (P <0.05). The analgesic rate was 100% in group A and 38 %, There was a significant difference between the two groups (P <0.05). Patients in group A were unconscious during surgery, patients were out of hospital longer than group B, there was significant difference between the two groups (P <0.05) No significant difference. Conclusion: A group of abortion analgesic effect is better than the B group is more suitable for painless abortion.