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作者曾用相当简单的模型测定了肾上腺一性腺系统的相互作用,大鼠去睾丸后24小时内,LH和FSH的分泌量均增加,并且促性腺细胞发生形态变化,阉割后12小时内去掉肾上腺,可阻断分泌和形态变化。最近实验表明,可的松本身可抑制去睾丸诱导的LH应答,而对FSH作用很小、本研究是为了揭示去肾上腺和/或可的松是否直接作用于大脑或脑垂体。 材料与方法:成年雄性大鼠分成正常组、阉割组和同时进行阉割及去肾上腺组。手术在上午8:00
The authors used a rather simple model to determine the adrenal gland-gonadal interaction. Excretion of LH and FSH was increased within 24 hours of testicular destroying in rats, and morphological changes of gonadotrophs were observed. Adrenal glands were removed within 12 hours after castration , Can block the secretion and morphological changes. Recent studies have shown that cortisone itself can inhibit the testicular-induced LH response, but little effect on FSH, this study is to reveal whether adrenal and / or cortisone directly acting on the brain or pituitary gland. MATERIALS AND METHODS: Adult male rats were divided into normal group, castration group and castration and adrenalectomy group. Surgery at 8:00 in the morning