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目的探讨减轻或消除患者静脉滴注华蟾素引起局部疼痛和静脉损伤的方法。方法选择接受华蟾素治疗的患者219例,随机分为观察组110例,对照组109例,观察组在静脉穿刺上方1 cm处沿血管方向贴止痛消炎膏;对照组按照常规穿刺固定,穿刺点上方不贴止痛消炎膏,对2组患者局部疼痛及皮肤有无红肿等情况,进行观察比较。结果观察组在静脉滴注华蟾素过程中,局部疼痛和皮肤红肿等症状明显减轻或消失,优于对照组,P<0.01。结论止痛消炎膏对防治静脉滴注华蟾素致静脉损伤有显著效果,且操作简便,值得临床推广应用。
Objective To explore ways to reduce or eliminate local pain and venous damage caused by intravenous infusion of cinobufacini in patients. Methods A total of 219 patients received cinobufotalin treatment were randomly divided into observation group (n = 110) and control group (n = 109). The observation group was given the analgesic anti-inflammatory cream 1 cm above the venous puncture and the control group was fixed by conventional puncture Top of the point is not posted pain and anti-inflammatory cream, the two groups of patients with local pain and skin redness and other conditions were observed and compared. Results During the intravenous drip of cinobufacini, the symptoms such as local pain and skin irritation of the observation group were significantly reduced or disappeared, which was better than that of the control group (P <0.01). Conclusion Analgesic anti-inflammatory cream for the prevention and treatment of intravenous infusion of cinobufacin induced venous injury have a significant effect, and easy to operate, worthy of clinical application.