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采用以家庭为单位的随机对照设计，在以肾综合征出血热野鼠型为主的混合型疫区，考核肾综合征出血热沙鼠肾细胞灭活疫苗（Ⅰ型）的现场效果。全程接种７８６６人，接种反应轻微。接种后两周血清中和抗体阳转率为４８．０％，滴度为５．９５；血清ＥＬＩＳＡ抗体阳转率为８１．３％，１年后降为２４．０％，加强接种后两周回升为８７．０％。接种后１年，全程接种组无一病例发生，而全程对照组有９例病例，疫苗保护率为１００％（６０．５％～１００％）。
A randomized, family-based design was used to evaluate the efficacy of inactivated vaccine against renal syndrome (HFRS) nephrotic syndrome in a mouse model of hemorrhagic fever with renal syndrome. Vaccination 7866 people throughout the vaccination reaction minor. Two weeks after inoculation, the seroconversion rate of serum neutralizing antibody was 48.0% and the titer was 5.95. The positive rate of serum ELISA antibody was 81.3% and decreased to 24.0% after one year, Weekly recovery was 87.0%. One year after inoculation, there was no case of inoculation in the whole course, while there were 9 cases in the whole course of control group. The vaccine protection rate was 100% (60.5% -100%).