哮喘持续状态时,常需要气管插管及机械通气。对这样的病人可能需用镇静药以减少焦虑,不适及非同步通气。本文报告2例哮喘持续状态和呼吸衰竭,尽管作了气管插管、机械通气,用了支气管插管、机械通气、用了支气管扩张药、激素和镇静药,但病情仍加重,给予静脉注射氟哌啶后,发现了支气管扩张有的力证据。例1。男性,67岁,有15年哮喘史,因哮喘持续状态而入院。插入气管导管后作机械通气。尽管应用了氨茶碱、氢可的松静注,羟异丙肾上腺素雾化吸入,必要时皮下注射肾上腺素等多种药物,治疗了10小时,支气管痉挛仍持续存在,吸气峰压(PlP)持续>50cmH_2O动脉血气分析显示pH7.24,PaCO_264托,PaO_280托。停β-激动药2h和皮质 Asthma persistence, often require endotracheal intubation and mechanical ventilation. Sedatives may be needed for such patients to reduce anxiety, discomfort and asynchrony. This article reports two cases of asthma persistence and respiratory failure, despite the presence of endotracheal intubation, mechanical ventilation, bronchial intubation, mechanical ventilation, bronchodilators, hormones and sedatives, but the condition is aggravated by intravenous fluorosis Piperidine, found some evidence of bronchiectasis. example 1. Male, 67 years old with 15 years history of asthma admitted to hospital due to asthma persistence. After insertion of the tracheal catheter for mechanical ventilation. Despite the application of aminophylline, hydrocortisone intravenous injection of hydroxy-isoproterenol inhalation, if necessary, subcutaneous injection of epinephrine and other drugs for 10 hours, bronchospasm persists, peak inspiratory pressure ( PlP) for> 50cmH2O arterial blood gas analysis showed pH7.24, PaCO_264 care, PaO_280 care. Stop β-agonist 2h and cortex