禽流感是由甲型禽流感病毒引起的急性传染病,近年来这种向来只威胁家禽生命的病毒已经打破种属障碍直接导致人类死亡。尤其是高致病性禽流感病毒H5N1亚型的出现,严重威胁人类健康。关于H5N1的形态,基因结构及编码蛋白质的功能研究已取得了较大进展,病毒致病性的研究也发展迅速。加强对人禽流感分子生物学的研究,对防控大流行有重要的意义。 Bird flu is an acute infectious disease caused by the A virus. In recent years, this virus, which has always threatened the life of poultry, has broken the genetic barrier and directly led to human death. In particular, the emergence of the H5N1 subtype of the highly pathogenic avian influenza virus poses a serious threat to human health. Research has been made on the morphology, gene structure and function of the encoded protein of H5N1, and the research on virus pathogenicity has also developed rapidly. Strengthening the research on the molecular biology of bird flu has great significance in preventing and controlling the pandemic.