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目的调查心血管高危住院患者抗血小板药物、他汀类药物和血管紧张素转化酶抑制剂(ACEI)的应用情况。方法测定5 254例50岁以上心血管高危的住院患者的踝臂指数(ABI),ABI<0.9诊断为下肢动脉疾病(PAD);将患者分成单纯PAD组、单纯冠心病(CHD)组、单纯缺血性脑卒中(IS)、单纯糖尿病(DM)组,PAD合并CHD或IS或DM组和参照组,分析各组用药情况。结果 5 254例患者中仅65.4%、36.9%、46.9%的患者接受抗血小板药物、他汀类药物和ACEI治疗。单纯PAD组中,3种药物单用和合用比例明显低于单纯CHD组;3药合用仅见于56%的CHD,8%的单纯IS,13%的单纯DM和21%的单纯PAD患者。结论 PAD治疗情况远远不如CHD,因此动脉粥样硬化不同表现形式及DM急需得到规范的强化治疗。
Objective To investigate the use of antiplatelet drugs, statins and angiotensin converting enzyme inhibitor (ACEI) in hospitalized patients with cardiovascular high risk. Methods The ankle-brachial index (ABI) of 5 254 hospitalized patients with cardiovascular risk over the age of 50 was determined. ABI <0.9 was diagnosed as lower extremity arterial disease (PAD). The patients were divided into simple PAD group, CHD group, Ischemic stroke (IS), simple diabetes mellitus (DM) group, PAD with CHD or IS or DM group and reference group, analysis of drug use in each group. Results Of the 5 254 patients, only 65.4%, 36.9% and 46.9% of patients received antiplatelet drugs, statins and ACEI. In the simple PAD group, the proportions of single and combined use of the three drugs were significantly lower than those of the simple CHD group. The combination of the three drugs was only seen in 56% of CHD, 8% of simple IS, 13% of simple DM and 21% of simple PAD. Conclusion PAD treatment is far less than CHD, so the different forms of atherosclerosis and DM urgently needed to be standardized intensive treatment.