目的探讨无创正压通气在慢性阻塞性肺疾病所致呼吸衰竭中的应用效果。方法本院从2010年2月到2012年3月共收治慢性阻塞性肺疾病所致呼吸衰竭患者80例,将其随机分为观察组和对照组,观察组的40例患者和对照组的40例患者均进行常规治疗,在此治疗的基础上,观察组的患者给予无创正压通气,对照组的患者不给予特殊处理,比较两组患者在治疗前后的临床症状表改善情况。结果观察组患者的临床症状改善情况要明显优于对照组,其差异具有统计学意义(P<0.05)。结论对于慢性阻塞性肺疾病所致呼吸衰竭的患者,通过实施无创正压通气方法,可以有效改善患者的临床症状,有效阻止病情发展,并缩短住院时间,值得临床进一步推广应用。 Objective To investigate the application of non-invasive positive pressure ventilation in respiratory failure caused by chronic obstructive pulmonary disease. Methods From February 2010 to March 2012, 80 cases of respiratory failure caused by chronic obstructive pulmonary disease were treated in our hospital. They were randomly divided into observation group and control group, 40 cases in observation group and 40 cases in control group Patients were routinely treated. On the basis of this treatment, patients in observation group were given noninvasive positive pressure ventilation, and patients in control group were given no special treatment. The improvement of clinical symptoms before and after treatment was compared between the two groups. Results The improvement of clinical symptoms in observation group was better than that in control group, and the difference was statistically significant (P <0.05). Conclusion In patients with respiratory failure caused by chronic obstructive pulmonary disease, noninvasive positive pressure ventilation can effectively improve the clinical symptoms, effectively prevent the progression of the disease and shorten the length of stay, which is worth further clinical application.