论文部分内容阅读
目的：通过测定人咽喉部乳头状瘤组织中乳头状瘤病毒（ＨＰＶ）壳蛋白抗原及ＤＮＡ序列，探讨ＨＰＶ感染与咽喉部乳头状瘤的关系。方法：应用免疫组织化学方法（ＡＢＣ法）及ＤＮＡ斑点杂交技术。结果：２２例乳头状瘤组织ＨＰＶ抗原阳性率４５５％，ＨＰＶＤＮＡ阳性率５０％，并与组织学观察进行对比分析。结论：实验结果提示，人咽喉部乳头状瘤的发生和发展与ＨＰＶ感染有关系。
OBJECTIVE: To determine the relationship between papillomavirus (HPV) coat protein antigen and DNA sequence in human papilloma papilloma and explore the relationship between HPV infection and papilloma of the throat. METHODS: Immunohistochemistry (ABC method) and DNA dot blotting techniques were used. RESULTS: The positive rate of HPV antigen in 45 cases of papilloma was 45.5%, and the positive rate of HPV DNA was 50%. The results were compared with histological observation. Conclusion: The experimental results suggest that the occurrence and development of human papilloma pharynx is related to HPV infection.