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[目的]通过对8例人类免疫缺陷病毒/艾滋病(HIV/AIDS)患者进行中西医结合干预治疗,观察其临床疗效。[方法]8例HIV/AIDS患者在服用西药抗病毒药物双汰芝(AZT+3TC)、奈韦拉平(NVP)的同时给予中药扶正排毒胶囊,疗程6个月,治疗前后记录症状体征积分,并检测T细胞亚群、病毒载量以及丙氨酸转氨酶(ALT)、谷草转氨酶(AST)、肌酐(CR)、血液尿素氮(BUN)和体质量。[结果]治疗后症状体征积分较疗前明显下降(P<0.05),CD4计数有一定的升高(P>0.05),病毒载量在治疗6个月后全部低于检测下限;ALT恢复至正常范围;体质量保持稳定(P>0.05)。[结论]通过中西医结合干预治疗,可显著改善艾滋病患者的症状,提高免疫功能,抑制HIV的复制,降低西药的毒副作用。
[Objective] To observe the clinical effect of 8 cases of human immunodeficiency virus / AIDS (HIV / AIDS) treated with integrated traditional Chinese and western medicine. [Method] 8 cases of HIV / AIDS patients were given Fuzheng detoxification capsules simultaneously with AZT + 3TC and NVP. The course of treatment was 6 months. The scores of symptoms and signs were recorded before and after treatment T cell subsets, viral load, and alanine aminotransferase (ALT), aspartate aminotransferase (AST), creatinine (CR), blood urea nitrogen (BUN) and body mass. [Results] The score of symptom and sign after treatment was significantly lower than before treatment (P <0.05), and the CD4 count increased to a certain extent (P> 0.05). The viral load was lower than the detection limit after 6 months of treatment. Normal range; body weight remained stable (P> 0.05). [Conclusion] Integrative treatment can significantly improve the symptoms of AIDS patients, improve immune function, inhibit HIV replication and reduce the side effects of western medicine.