患者　男,42岁。因全身乏力半个月,加重伴精神恍惚5天于1999年11月5日入院。曾于1998年10月22日因直肠癌经腹会阴根治+结肠造瘘术。病理诊断:直肠乳头状腺癌。术后4次行ＦＩＶＢ方案化疗。1999年9月开始单服卡莫氟,剂量200ｍｇ,3次/天,服用至45天时无诱因突然出现双下肢无力,易 Male patient, 42 years old. Due to generalized fatigue half a month, increased with trance 5 days in November 5, 1999 admission. Had on October 22, 1998 due to rectal cancer via abdominal perineal radical colostomy. Pathological diagnosis: rectal papillary adenocarcinoma. Four postoperative FIVB regimen chemotherapy. September 1999, a single dose of carmofur dose 200mg, 3 times / day, taking 45 days without cause suddenly appeared in both lower extremities weakness, easy