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镎-237引起的生物效应受各种因素的影响。Kreslov等人在相同的条件下,分别给大鼠腹腔注入和静脉注入1.5mg的镎—237。结果是:静脉注入后5—7天有50％的大鼠死亡;而腹腔注入后没有一例死亡。可见注入途径对生物效应的影响,静脉注入的毒性高于腹腔注入。 Levdik等人给大鼠静脉注入5.1μCi/kg体重的硝酸镎,在最初2—5天有17％的大鼠死亡;以相同的剂量静脉注入草酸镎以后,没有一例死亡。可见不同的化学
The biological effects of technetium-237 are affected by various factors. Kreslov et al. Injected and intravenously infused 1.5 mg of Beta-237 into the abdominal cavity of the rat under the same conditions. As a result, 50% of rats died 5-7 days after intravenous injection, and none of them died after intraperitoneal injection. The effect of the injection route on biological effects can be seen, and the intravenous injection toxicity is higher than that of intraperitoneal injection. Levdik et al. Infusing rats with guanidine nitrate at a dose of 5.1 μCi/kg body weight, and 17% of the rats died on the first 2-3 days; after intravenous infusion of oxalic acid oxime at the same dose, none died. Different chemistry can be seen