放疗是肿瘤的主要治疗手段之一,长期以来,国内外针对提高肿瘤疗效进行了多方努力,但总的疗效改变不明显。放射抗拒一直是制约肿瘤放疗疗效的瓶颈,是放疗失败的主要原因之一。放疗效果与肿瘤、宿主及肿瘤和正常组织的放射剂量效应有关。目前采用的各种肿瘤放疗,大多是不同个体使用相似的放疗方案,但是不同个体放射敏感性有明显差异,因此,预测肿瘤放射抗拒性针对不同个体采用不同的放疗方案具有 Radiation therapy is one of the main treatments of cancer. For a long time, many efforts have been made to improve the efficacy of cancer at home and abroad, but the overall curative effect has not changed obviously. Radiation resistance has been the bottleneck restricting the efficacy of tumor radiotherapy and is one of the main reasons for the failure of radiotherapy. The radiotherapy effect is related to the radiation dose effect of the tumor, host, tumor and normal tissue. Currently used in a variety of tumor radiotherapy, mostly different individuals using similar radiotherapy programs, but different individuals have significant differences in radiosensitivity, therefore, the prediction of tumor radioresistance for different individuals using different radiotherapy programs have