论文部分内容阅读
自1985年Rubin等发现可溶性白细胞介素2受体(SIL-2R)以来,已经证实许多免疫功能异常的疾病中存在SIL-2R的变化。但有关流行性出血热(EHF)患者SIL-2R变化与肾脏损害的关联研究报道尚少。我们动态检测了20例EHF患者血清SIL-2R水平,并观察其与肾脏损害的关系,以探讨SIL-2R在EHF发病中的作用及其与肾脏损害关联的临床意义。
Since the discovery of soluble interleukin 2 receptor (SIL-2R) by Rubin et al. In 1985, it has been demonstrated that there are SIL-2R changes in many immunocompromised diseases. However, there are few reports on the association between SIL-2R changes and renal damage in patients with epidemic hemorrhagic fever (EHF). We detected the serum levels of SIL-2R in 20 EHF patients and observed the relationship between SIL-2R and renal damage in order to explore the role of SIL-2R in the pathogenesis of EHF and its clinical significance associated with renal damage.