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细菌性腹膜炎目前仍是腹部外科的棘手问题。传统治疗包括补液、静脉输注抗生素、手术去除污染源及清洗腹腔。但如果腹腔已有明显污染,则这种疗法似嫌不足。腹膜腔灌洗不是新的治疗方法,在本世纪初已开始应用。当前腹膜透析慢性治疗的患者在有腹膜炎时肾病学家常用含抗生素的治疗性连续腹膜腔灌洗。但有些外科医师顾虑持续腹膜腔灌洗可能使感染扩数,影响白细胞功能,危及宿主的防御系统。为了解决连续腹膜腔灌洗究竟有害还是有益的问题,作者用120只家兔进行实验。实验性腹膜炎用高浓度或低浓度二种人粪液注入腹腔做成模型。灌洗液为乳酸钠林格氏溶液,灌洗速度为40～50ml/小时。庆
Bacterial peritonitis is still a thorny problem in abdominal surgery. Traditional treatments include rehydration, intravenous infusion of antibiotics, surgical removal of sources of contamination and cleansing of the abdominal cavity. However, if the abdominal cavity has been significantly contaminated, then this treatment seems inadequate. Peritoneal lavage is not a new treatment and has been used since the turn of the century. In patients with chronic peritoneal dialysis, nephrologists often use therapeutic continuous peritoneal lavage with antibiotics when there is peritonitis. However, some surgeons are concerned that persistent peritoneal lavage may increase the number of infections, affect leukocyte function and compromise the host’s defense system. In order to solve the problem of whether continuous peritoneal lavage is harmful or beneficial, the authors used 120 rabbits for experiments. Experimental peritonitis with high concentration or low concentration of two kinds of human fluid into the abdominal cavity model. The lavage solution is sodium lactate Ringer’s solution, lavage rate of 40 ~ 50ml / hour. Celebration