超抗原主要分为①细菌性;②病毒性。与MHCⅡ类分子结合,可使TCRβ链上特定可变部位Ⅴβ表现的极大量T细胞全部活化。任何一组超抗原,由于活化T细胞而参与感染性疾病的发病机制。最近,发现了几例新的细菌性超抗原,本文只就与超抗原的病原性这一热门话题作一报告。1.细菌性超抗原 Superantigens are mainly divided into ① bacteria; ② viral. In combination with MHC class II molecules, a very large number of T cells in the Vβ domain of a specific variable portion of the TCR β chain are all activated. Any group of superantigens that are involved in the pathogenesis of infectious diseases due to activated T cells. Recently, several new bacterial superantigens have been identified and this article reports only on a hot topic with the pathogenicity of superantigens. Bacterial superantigen