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散在病例中自身免疫现象与卵巢早衰的联系和卵巢早衰妇女血清中发现针对卵巢的抗体提示本病的发病机理中存在免疫机制。作者描述1例血清促性腺激素升高,雌激素减少的卵巢早衰病人作卵巢活检证实有淋巴细胞浸润,用强的松治疗产生暂时性月经恢复。病例报告:病人22岁,继发闭经3年。初潮11岁,周期26～31天。闭经后用雌激素孕酮周期治疗可引起规则的撤退性出血,停药后又闭经并有频繁潮热。体检无明显异常,蝶鞍多向X片正常。妇科
Scattered cases of autoimmune phenomena associated with premature ovarian failure and premature ovarian failure in women’s serum antibodies to ovarian antibodies suggest that the pathogenesis of this disease exists in the immune mechanism. The authors describe a case of ovarian biopsy with elevated serum gonadotropin and estrogen-reduced premature ovarian failure confirmed by lymphocytic infiltration and treatment with prednisone to produce temporary menstrual recovery. Case report: Patient 22 years old, secondary to amenorrhea for 3 years. Menarche 11 years old, cycle 26 ~ 31 days. After amenorrhea estrogen progesterone cycle treatment can cause regular withdrawal bleeding, amenorrhea and frequent hot flashes after stopping. No obvious physical examination, septal multidirectional X-sheet normal. Gynecology