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目的:对单中心3年内所有全皮下植入型心律转复除颤器(S-ICD)患者的应用情况进行分析。方法:纳入2016年12月至2020年8月在浙江绿城心血管病医院心脏中心植入S-ICD的所有患者,统计并分析植入适应证、术前体表心电图筛查、术中麻醉方式和效果、除颤阈值(DFT)测试、并发症及术后随访情况。结果:共成功植入S-ICD 11例,其中3例(27.3%)为移除原经静脉植入型心律转复除颤器(TV-ICD)后改植入S-ICD;均为男性,年龄12~68(39.7±15.3)岁,体重指数(24.0±3.9) kg/mn 2;随访时间1~44(19.2±16.8)个月。手术时间(69.0±19.1) min,术中测试除颤阻抗(53.6±8.0) Ω,室性心律失常诱发后诊断至成功除颤时间(12.9±1.7) s。1例患者(9.1%)行局部麻醉,术后疼痛评分(VAS)6分;10例(90.9%)行局部麻醉+静脉镇静,VAS(3.0±0.9)分。所有患者未发生严重并发症。随访发现:识别室性心律失常事件[室性心动过速/心室颤动(VT/VF)]并正确治疗2例,识别VT/VF因自行终止而未治疗1例,出现误感知但未治疗1例。n 结论:S-ICD为年轻的猝死高风险患者及移除TV-ICD需再次植入患者的适应证之一,术中局部麻醉联合静脉镇静安全有效,诱发VF时间延长至8 s可能有助于成功DFT测试。“,”Objective:Subcutaneous implantable cardioverter defibrillator (S-ICD) is a new method for prevention of sudden cardiac death. We intended to analyze the application of all S-ICD patients in our center within three years.Methods:All patients who were implanted with S-ICD at the Heart Center of Zhejiang Greentown Cardiovascular Hospital from December 2016 to August 2020 were counted and analyzed for indications for implantation, pre-operative surface electrocardiogram screening, intraoperative anesthesia methods and effects, defibrillation threshold (DFT) test, complications, and follow-up.Results:Eleven male were implanted successfully, age were 12-68 (39.7±15.3) years old, and body mass index were (24.0±3.9) kg/mn 2, 3 cases were implanted after removing the original intravenously implanted cardioverter defibrillation defibrillator (TV-ICD) ; The follow-up time was 1-44 (19.2±16.8) months. The average operation time was about (69.0±19.1) min, mean intra operative defibrillation impedance was (53.6±8.0) Ω, and the time from induction of ventricular arrhythmia to successful defibrillation was (12.9±1.7) s. One patient (9.1%) underwent local anesthesia, and the postoperative pain score (VAS) was 6 points; 11 Patients (90.9%) underwent local anesthesia plus intravenous sedation, and mean VAS was (3.0±0.9) points. No severe complications occurred, and a large area of purpuric ecchymosis occurred in one patient. During the follow-up, one patient developed ventricular arrhythmia event [ventricular tachycardia/ventricular fibrillation (VT/VF) ]was treated in 1 case. Identified 1 case of VT/VF and received the correct treatment. VT/VF were identified in 1 case and untreated because of self-termination. One case of misperception but not treated.n Conclusion:S-ICD is suitable for young patients with high risk of sudden death and patients who have removed original TV-ICD. Local anesthesia combined with intravenous sedation is safe and effective. Increasing the time of VF induced to 8 seconds may be helpful to do DFT test successfully.