昏迷在临床上是常见的,一般都能作出正确诊断与处理。但有时亦可能遇到某些特殊情况,其中之一就是所谓“闭锁综合征”。在“闭锁综合征”患者,由于除了不完全的眼球和眼睑动作以外全身瘫痪,压眶无反应,又不能说话,因此有可能误认为昏迷。然而,我们如果掌握了这个综合征的特点,就可以很容易的发现,患者实际上是清醒的,他可以通过睁眼和闭眼示意。自1966年Plum与Posner首先应用闭 Coma is clinically common, and generally can make the correct diagnosis and treatment. But sometimes it may encounter some special circumstances, one of which is the so-called “lock syndrome.” In patients with “lock syndrome,” because of incomplete paralysis of the eyeballs and eyelids, the orbital reflex does not respond and can not speak, so it may be mistaken for a coma. However, if we grasp the characteristics of this syndrome, we can easily find out that the patient is actually awake and he can express his eyes open and closed eyes. Since 1966 Plum and Posner first closed