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干扰现象是病毒工作中常遇到的重要问题。Isaacs 和 Lindenman 二氏于1957年发现悬浮培养于 Earle 氏缓冲盐溶液中的鸡胚绒毛尿囊膜经接种灭活流感病毒后,能产生并释放出一种干扰病毒的物质,其理化性状均不同于病毒、抗原或抗体,称之为干扰素(Interferon)。一、干扰素的特征干扰素可能是宿主细胞被病毒侵入后在胞浆内形成的一种产物其成分是一种分子量(62000—70000)较小的蛋白质,含少量
Interference is an important issue often encountered in the work of the virus. In 1957, Isaacs and Lindenman discovered that chick chorioallantoic membrane suspension culture in Earle’s buffer solution inoculated with inactivated influenza virus can produce and release a virus-interfering substance with different physical and chemical properties In the virus, antigen or antibody, called Interferon (Interferon). First, the characteristics of interferon Interferon may be the host cell invasion by the virus in the cytoplasm formed after a product whose composition is a molecular weight (62000-70000) smaller protein, with a small amount