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除在某些高度危险的病员外,氯胺酮极少引起心律不齐。通常它能维持血压及脉率,但是,氯胺酮的升压及心动过速作用,在任何剂量均可致严重的不利。作者研究了89例儿童接受小的牙科或眼科手术时,应用2毫克/公斤静注和10毫克/公斤肌注时的心血管系统变化,以阐明氯胺酮对心血管的影响。第一组74例,年龄1～12岁氯胺酮10毫克/公斤肌注。本组中年龄大于四岁者,术前给阿托品0.008毫克/公斤肌注。第二组10例,年龄4～12岁氯胺酮2毫克/公斤静注。第三组5例,年龄4～12岁氯胺酮2毫克/公斤静注。并术前阿托品0.008毫克/公斤静注。
Apart from some highly dangerous patients, ketamine rarely cause arrhythmia. Normally it maintains blood pressure and pulse rate, however, the effects of elevated ketamine and tachycardia can be severe at any dose. The authors studied changes in cardiovascular system in 89 children receiving small dental or ophthalmic surgery with 2 mg / kg intravenous injection and 10 mg / kg intramuscular injection to elucidate the cardiovascular effects of ketamine. The first group of 74 patients aged 1 to 12 years ketamine 10 mg / kg intramuscular injection. In this group of people over the age of four, preoperative atropine 0.008 mg / kg intramuscular injection. The second group of 10 patients, aged 4 to 12 years ketamine 2 mg / kg intravenous injection. The third group of 5 patients, aged 4 to 12 years ketamine 2 mg / kg intravenous injection. And preoperative atropine 0.008 mg / kg intravenous injection.