目的:观察评价赖诺普利在高原地区治疗高血压病的降压疗效及血压波动情况.方法:对90例高血压患者给予赖诺普利(10～30)mg,观察8周。在治疗期开始时以及治疗期的第2周、第8周行24小时动态血压监测,评价疗效。结果:降压主要降幅在前2周,显效42例(47%),有效21例(23%),总有效率占70%;谷峰比率(T/P)为0.61。结论:在高海拔地区赖诺普利治疗轻中度高血压病疗效好,副作用少,值得推广。 OBJECTIVE: To observe and evaluate the antihypertensive efficacy and blood pressure fluctuation of lisinopril in the treatment of hypertension in the plateau area.Methods: Lisinopril (10 ~ 30) mg was given to 90 hypertensive patients for 8 weeks. At the beginning of the treatment period and the second and eighth weeks of treatment, 24-hour ambulatory blood pressure monitoring was performed to evaluate the efficacy. Results: The major decrease of blood pressure in the first two weeks was markedly effective in 42 cases (47%), effective in 21 cases (23%), total effective rate in 70% and trough / peak ratio (T / P) CONCLUSIONS: Lisinopril at high altitude is effective and has few side effects in the treatment of mild to moderate essential hypertension and is worth promoting.