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目的探讨纳米羟基磷灰石聚酰胺66(n-HA/PA66)复合人工椎体治疗胸腰椎椎体肿瘤中的应用价值。方法自2003年12月至2005年9月,对14例胸腰椎肿瘤患者行胸腰椎前路椎体切除、复合人工椎体植入、前路钉板内固定术。男性9例,女性5例,年龄32~68岁,平均50岁。T112例;T122例;L15例;L25例。病理学诊断:动脉瘤样骨囊肿3例,血管瘤5例,骨巨细胞瘤2例,转移瘤3例。结果术后随访3~18个月,平均10个月,复合人工椎体植骨融合率85.7%,无内固定松动及螺钉断裂,所有病例存活至今。结论彻底切除胸腰椎肿瘤,通过椎体间人工椎植入内固定重建脊柱的稳定性,疗效满意。复合人工椎体具有良好的生物相容性,植入融合率高,牢固可靠,是理想的骨移植替代材料。
Objective To investigate the application of nano-hydroxyapatite polyamide 66 (n-HA/PA66) composite artificial vertebral body in the treatment of thoracolumbar vertebral body tumors. Methods From December 2003 to September 2005, 14 cases of thoracic and lumbar vertebrae were treated with thoracolumbar anterior corpectomy, composite artificial vertebral body implantation, and anterior screw plate internal fixation. There were 9 males and 5 females, aged 32-68 years, with an average age of 50 years. T112 cases; T122 cases; L15 cases; L25 cases. Pathological diagnosis: 3 cases of aneurysmal bone cyst, 5 cases of hemangiomas, 2 cases of giant cell tumor of bone, and 3 cases of metastases. Results The follow-up period was 3 to 18 months, with an average of 10 months. The fusion rate of the composite artificial vertebral body was 85.7%. There was no internal fixation loosening and screw fracture. All the cases survived to this day. Conclusion The thoracolumbar tumors were completely resected and the stability of the spine was reconstructed by artificial intervertebral vertebral fixation. The curative effect was satisfactory. Composite artificial vertebral body has good biocompatibility, high implant fusion rate, solid and reliable, it is an ideal bone graft alternative material.