文章综述了目前头颈部肿瘤标记物的性质、来源、用途和缺陷。大多数标记物特异性和敏感性不高。但是治疗前标记物升高的病人,经过连续测定有助于衡量治疗效果。潜在用途如:确定早期复发、转移和估计预后,多个指标能提高诊断准确率。有的标记物还与病人的免疫抑制状态有关。 The article reviews the nature, origin, use, and deficiencies of current head and neck tumor markers. Most markers are not specific and sensitive. However, in patients with elevated markers before treatment, continuous measurements can help measure therapeutic effects. Potential uses such as identifying early recurrence, metastasis, and estimating prognosis, multiple indicators can improve diagnostic accuracy. Some markers are also related to the patient’s immunosuppressive state.