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头颈部非何杰金氏淋巴瘤并不常见,其确切的发病率尚不清楚。Freeman曾报道1467例病人,其中仅2％位于口腔。头颈部何杰金氏病主要累及淋巴结,很少波及腺外组织如腭骨及骨。非何杰金氏淋巴瘤则不同,很易累及淋巴腺外组织。 1966年Rappaport按细胞的类型及排列将非何杰金氏淋巴瘤分为三类:淋巴细胞型、组织细胞型及混合型(又称未分化型)。以后,Schnitzer和Weaver又加以改进,把未分化型进一步分为Burkitts型和非Burkitts型。然而
Non-Hodgkin’s lymphoma in the head and neck is not common, and its exact incidence is unclear. Freeman has reported 1467 patients, of whom only 2% are in the mouth. Hodgkin’s disease of the head and neck mainly involves lymph nodes and rarely affects extra-glandular tissues such as the sacrum and bone. Non-Hodgkin’s lymphoma is different, it is easy to involve the lymphatic tissue. In 1966, Rappaport classified non-Hodgkin’s lymphomas into three types according to the type and arrangement of cells: lymphocyte type, histiocytic type, and mixed type (also called undifferentiated type). Later, Schnitzer and Weaver further improved the undifferentiated type into Burkitts and non-Burkitts types. however