目的 :探讨封髓丹颗粒剂抗口腔溃疡及镇痛抗炎作用。方法 :给动物灌服封髓丹颗粒剂 (0 .5 ,5 .0 ,10 .0g·kg-1)。动物口腔溃疡分别系由皮下注射白色葡萄球菌及石炭酸烧灼而成。应用醋酸扭体法、热板法、二甲苯致耳郭炎症及足肿胀法。结果与结论 :实验数据表明该方药具有抗口腔溃疡作用 ,可加速溃疡面积缩小及愈合 ,并具有镇痛抗炎作用 ,且量效关系规律。 Objective : To investigate the anti-oral ulcer, analgesic and anti-inflammatory effects of Fengsuidan granules. Methods : The animals were given Guansuidan granules (0.5, 5.0, 10.0g·kg-1). Animal oral ulcers were made by subcutaneous injection of Staphylococcus aureus and carbolic acid. Acetic acid writhing method, hot plate method, xylene induced ear inflammation and foot swelling method. Results and conclusions: The experimental data show that the prescription has anti-oral ulcer effects, which can accelerate the shrinkage and healing of the ulcer area, and has analgesic and anti-inflammatory effects, and the dose-effect relationship.