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目的:研究幽门螺旋杆菌(Hp)感染与铁缺乏的相关性。方法:收集2008年5月~2011年9月住院及门诊94例C13检查患儿血样,进行血常规、铁代谢检查。分析比较C13阳性的Hp现症感染患者与C13阴性的患者血红蛋白(Hb)、血清铁(SI)、铁蛋白(SF)、平均红细胞体积(MCV)、平均血红蛋白含量(MCH)、平均血红蛋白浓度(MCHC)等指标,进一步探讨Hp现症感染患者中铁缺乏及缺铁性贫血的发生情况。结果:Hp感染组与非感染组Hb、MCV、MCH、SI、SF差异有统计学意义(P<0.05);缺铁性疾病发生率分别为68%、29%,P<0.01,Hp感染会使患儿发生缺铁性疾病的风险增加。结论:Hp感染与儿童铁缺乏或缺铁性贫血有相关性。
Objective: To study the relationship between Helicobacter pylori (Hp) infection and iron deficiency. Methods: Blood samples were collected from 94 children with C13 inpatients and outpatients from May 2008 to September 2011, and blood and iron metabolism were examined. The levels of hemoglobin (Hb), serum iron (SI), ferritin (SF), mean corpuscular volume (MCV), mean hemoglobin content (MCH), and mean hemoglobin concentration in patients with C13-positive Hp infection and those with C13- MCHC) and other indicators to further explore the Hp infection in patients with iron deficiency and iron-deficiency anemia. Results: The differences of Hb, MCV, MCH, SI and SF between Hp infection group and non-infected group were statistically significant (P <0.05). The incidence of iron deficiency disease was 68%, 29%, P < The risk of iron deficiency disease in children increased. Conclusions: Hp infection is associated with iron deficiency or iron deficiency anemia in children.