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目的探讨气管插管技术的合理应用对羊水胎粪污染新生儿转归和预后的影响。方法将810例出生时有活力的羊水胎粪污染新生儿随机按是否气管内吸引分为实验组和对照组,实验组392例新生儿,生后即给予气管内吸引;对照组418例新生儿,生后仅给予常规气道清理。结果实验组胎粪吸入综合征发病率9.29%,新生儿窒息率2.04%,其他肺部疾病发病率4.59%;对照组胎粪吸入综合征发病率2.63%,新生儿窒息率1.44%,其他肺部疾病发病率5.26%。两组均无新生儿缺氧缺血性脑病和死亡病例。结论有活力的羊水胎粪污染新生儿无论是否气管内吸引,胎粪吸入综合征发病率、新生儿窒息率、其他肺部疾病发病率、死亡率和新生儿缺氧缺血性脑病发病率等不良预后均无统计学差异。所以,对于有活力的羊水胎粪污染新生儿,不给予气管内吸引不会影响其预后,同时可减少不必要的气管插管副作用。
Objective To investigate the effect of rational intubation of tracheal intubation on the outcome and prognosis of neonates with meconium-stained amniotic fluid. Methods 810 neonates with viable meconium-stained amniotic fluid were randomly divided into experimental group and control group according to the endotracheal attraction. In the experimental group, 392 newborns were given endotracheal intubation. In the control group, 418 newborns After birth, only give regular airway clearance. Results The incidence of meconium aspiration syndrome in experimental group was 9.29%, the rate of neonatal asphyxia was 2.04%, the incidence of other pulmonary diseases was 4.59%. The incidence of meconium aspiration syndrome in control group was 2.63%, neonatal asphyxia rate was 1.44% Ministry of disease incidence of 5.26%. Neonatal hypoxic-ischemic encephalopathy and deaths were absent in both groups. CONCLUSIONS: Neonates with viable meconium-stained amniotic fluid have higher rates of neonatal hypoxic-ischemic encephalopathy, such as intra-tracheal aspiration, incidence of meconium aspiration syndrome, neonatal asphyxia, incidence of other pulmonary diseases, mortality and neonatal hypoxic-ischemic encephalopathy No significant difference in prognosis. Therefore, the vigorous amniotic fluid meconium pollution of newborns, do not give endotracheal suction will not affect its prognosis, while reducing unnecessary side effects of tracheal intubation.