论文部分内容阅读
目的探讨生殖免疫检测对不孕不育患者的临床应用。方法根据不孕不育原因将230例患者分为原发不孕组,继发不孕组和自然流产组。检测三组患者抗子宫内膜抗体(EmAb)、抗心磷脂抗体(ACAb)、抗卵巢抗体(AOAb)、抗透明带抗体(ZPAb)、抗绒毛膜促性腺激素抗体(AhAb)、抗滋养层抗体(TAAb)、抗精子抗体(AsAb)阳性率情况。结果 AsAb和EmAb检测的阳性率最高,分别为29.1%和27.0%;原发不孕组AsAb阳性率最高,EmAb阳性率最低,组间比较差异有统计学意义(P<0.05);ACAb阳性率自然流产组最高,原发不孕组性率最低,AOAb阳性率原发不孕组明显高于继发不孕组和自然流产组,差异有统计学意义(P<0.05);AhAb阳性率继发不孕组最高,原发不孕组性率最低,三组间差异有统计学意义(P<0.05)。结论不孕不育患者体内均存在EmAb、ACAb、AOAb、ZPAb、AhAb、TAAb、AsAb异常,不同类型不孕不育抗体阳性率不同。
Objective To investigate the clinical application of reproductive immunity in infertility patients. Methods According to the causes of infertility, 230 patients were divided into primary infertility group, secondary infertility group and spontaneous abortion group. Three groups of patients were tested for anti-CEA, ACAb, AOAb, ZPAb, AhAb, anti-trophoblast Antibodies (TAAb), anti-sperm antibody (AsAb) positive rate of the situation. Results The positive rates of AsAb and EmAb were the highest (29.1% and 27.0%, respectively). The positive rates of AsAb and EmAb were the lowest in primary infertility group (P <0.05). The positive rate of ACAb The highest rate of spontaneous abortion group, the lowest rate of primary infertility group, AOAb positive rate of primary infertility group was significantly higher than the secondary infertility group and spontaneous abortion group, the difference was statistically significant (P <0.05); AhAb positive rate following The highest incidence of infertility group, the lowest rate of primary infertility group, the difference between the three groups was statistically significant (P <0.05). Conclusion There are abnormalities of EmAb, ACAb, AOAb, ZPAb, AhAb, TAAb and AsAb in infertile patients. The positive rates of different types of infertility antibodies are different.