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目的探讨新生儿重度高胆红素血症换血疗法的指征、方法及效果。方法对15例重度高胆红素血症新生儿采用外周动静脉同步换血治疗,监测换血前后血清胆红素、血生化、血糖、CRP的变化。结果换血前后血清总胆红素和间接胆红素水平相比有统计学意义(P<0.01),换血前后血生化、血糖、CRP指标稳定。结论外周动静脉同步换血治疗是抢救治疗重度新生儿高胆红素血症简便、安全、有效的方法。
Objective To investigate the indications, methods and effects of transfusion therapy for neonatal severe hyperbilirubinemia. Methods 15 neonates with severe hyperbilirubinemia were treated with synchronized peripheral arterial and venous transfusion to monitor the changes of serum bilirubin, blood biochemistry, blood glucose and CRP before and after blood transfusion. Results Before and after the exchange of blood serum total bilirubin and indirect bilirubin levels were statistically significant (P <0.01), before and after blood exchange blood biochemical, blood glucose, CRP indicators stable. Conclusions Peripheral arteriovenous exchange transfusion is a simple, safe and effective method for salvage and treatment of severe neonatal hyperbilirubinemia.