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目的:通过对乳腺癌肿瘤血供的研究,为动脉灌注化疗奠定基础。材料与方法:6例乳腺癌患者,采用Seldinger技术,行锁骨下动脉造影,然后选择性动脉内灌注ADM60mg,CDDP80mg,MMC12~18mg。结果:(1)肿瘤主要血供50%来自胸廓外侧动脉,肩胛下动脉及胸廓内动脉各占25%,与以往观点不同;(2)6例乳腺癌经动脉灌注后原发灶及淋巴结均明显缩小。结论:乳腺癌的供血主要是胸廓外侧动脉,其次为肩胛下动脉及胸廓内动脉。作者提出行动脉灌注化疗时,不宜只行胸廓内动脉,而应以上3支动脉一起灌注,才可获得更佳疗效
Objective: To lay a foundation for arterial infusion chemotherapy by studying the blood supply of breast cancer. Materials and Methods: Six patients with breast cancer underwent subclavian artery angiography with Seldinger technique, then selective arterial infusion of ADM 60 mg, CDDP 80 mg, and MMC 12-18 mg. Results: (1) The main blood supply of the tumor was 50% from the lateral thoracic artery, 2% from the inferior scapular artery and internal thoracic artery, which was different from previous views; (2) The primary tumor and lymph node were found in 6 cases of breast cancer after transcatheter arterial infusion. Obviously reduced. Conclusion: The blood supply of breast cancer is mainly the lateral thorax artery, followed by the inferior scapular artery and the internal thoracic artery. The authors propose that when intra-arterial infusion chemotherapy is performed, it is not advisable to only perform internal thoracic arterial vasculature, and that the above three iliac arteries should be perfused together for better efficacy.