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目的:测定正常成人血清Prohepcidin浓度,分析影响血清Prohepcidin水平的相关因素。方法:测定21例正常成人血清Prohepcidin浓度,观察分析其与高敏C反应蛋白、白细胞介素-6、促红细胞生成素、血红蛋白和丙氨酸氨基转移酶等指标之间的关系。结果:正常成人血清Prohepcidin浓度为(153.7±29.5)ng/mL,性别及不同年龄间比较差异无统计学意义(P>0.05)。正常成人血清Prohepcidin水平与促红细胞生成素浓度正相关。结论:促红细胞生成素可作为血清Prohepcidin的预测因子。
Objective: To determine the serum concentration of Prohepcidin in normal adults and analyze the related factors that affect the serum Prohepcidin level. Methods: Serum Prohepcidin levels were measured in 21 normal adults. The relationship between them was analyzed by high sensitivity C reactive protein, interleukin - 6, erythropoietin, hemoglobin and alanine aminotransferase. Results: The serum concentration of Prohepcidin in normal adults was (153.7 ± 29.5) ng / mL, there was no significant difference between sex and age (P> 0.05). Normal adult serum Prohepcidin levels are positively correlated with erythropoietin concentrations. Conclusions: Erythropoietin may serve as a predictor of serum Prohepcidin.