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目的:优选中风活心软胶囊的提取工艺。方法:采用水蒸气蒸馏法提取中风活心方中挥发油,以挥发油得率为指标,选取加水量、浸泡时间及蒸馏时间为考察因素,通过正交试验优选挥发油提取工艺;以葛根素含量为指标,选取加水量、煎煮时间及提取次数为考察因素,通过正交试验优化中风活心软胶囊的提取工艺。结果:最佳挥发油提取工艺为加6倍量水,不浸泡,蒸馏提取7 h;中风活心软胶囊的最佳水提取工艺为加10倍量水煎煮1.0 h,提取3次。结论:优选的提取工艺稳定可行,可推广于大生产应用。
Objective: To optimize the extraction process of Stroke Vitality Soft Capsule. Methods: Volatile oil was extracted by steam distillation and the yield of volatile oil was taken as an index. The amount of water added, soaking time and distillation time were selected as the investigation factors. Orthogonal test was used to optimize the extraction process of volatile oil. The content of puerarin , Select the amount of water, boiling time and the number of extraction as the investigation factors, through orthogonal test to optimize the stroke of soft capsules extraction process. Results: The optimal extraction process of volatile oil was 6 times of water, without soaking and distilled for 7 h. The optimal water extraction process of Zhongfeng Xinxin soft capsule was 10 times of boiling water for 1.0 h and extracted 3 times. Conclusion: The optimal extraction process is stable and feasible, which can be extended to large-scale production applications.